Rituximab
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Rituximab
Patients with cancer who take rituximab intravenous may be at a greater risk of getting a severe health problem called tumor lysis syndrome tlsthis may lead to death.
Rituximab. With the chemotherapy medicines fludarabine and cyclophosphamide. Rituximab sold under the brand name rituxan among others is a medication used to treat certain autoimmune diseases and types of cancer. Chronic lymphocytic leukemia cll. Rituximab sticks to all the cd20 proteins it finds.
Some brands of. Rituximab rituxan is a drug used to treat non hodgkins b cell lymphomas chronic lymphocytic leukemia granulomatosis with polyangiitis previously called wegeners granulomatosis microscopic polyangiitis and rheumatoid arthritis. Rituxan rituximab is a prescription medicine used to treat adults with. Find information about rituxan rituximab a possible treatment for ra nhl cll gpa mpa and pv.
Rituximab is used alone or in combination with other medicines to treat the following conditions in adults. Rituximab is used to treat certain types of cancer such as non hodgkins lymphoma chronic lymphocytic leukemiait works by slowing or stopping the growth of cancer cells. Upon binding to cd20 rituximab mediates b cell lysis. B cell non hodgkin lymphoma nhl that is cd20 positive.
Possible mechanisms of cell lysis include complement dependent cytotoxicity cdc. Rituximab is a monoclonal antibody that targets the cd20 antigen expressed on the surface of pre b and mature b lymphocytes. It targets a protein called cd20 on the surface of the leukaemia and lymphoma cells. Rituximab is a monoclonal antibody.
It is used alone in patients with follicular lymphoma or low grade lymphoma that has relapsed or is refractory doesnt respond to treatment. Non hodgkins lymphoma or chronic lymphocytic leukemia. Alone or with other chemotherapy medicines. Symptoms of granulomatosis with polyangiitis are fever joint pain fatigue and sinusitis.
It is used for non hodgkin lymphoma chronic lymphocytic leukemia rheumatoid arthritis granulomatosis with polyangiitis idiopathic thrombocytopenic purpura pemphigus vulgaris myasthenia gravis and epsteinbarr virus positive mucocutaneous ulcers. See important safety including boxed warnings for more information. People with serious infections should not receive rituxan.
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